Extraction and analysis of mango leaf components and testing their anti diabetic potential

Abstract

Diabetes is one of the life threatening metabolic disorders that has no cure but only management. Various therapeutic agents are available in nature which can aid in blood sugar management. However role of Mango in diabetes was always known to be negative and thought to increase blood sugar levels. Objective of the study is to test the therapeutic role of Mango leaf extract in diabetic control. The anti diabetic effect of leaf extract was studied based on the principle of alpha glucosidase enzyme inhibition test. Further, secondary metabolites present in leaf extract were analyzed biochemically. Antimicrobial potential of the extract was studied against 4 test bacteria which included Escherichia coli, Enterobacter spp, Pseudomonas aeroginosa and Staphylococcus aureus. Kirby bauer’s method of disc diffusion was used for this assay. All the results of the study were analyzed to confirm the therapeutic potential of mango leaves.