Helix - The Scientific Explorer | Peer Reviewed Bimonthly International Journal

Extraction and analysis of mango leaf components and testing their anti diabetic potential

Amita Kashyap — Mon, 31 Oct 2022 00:00:00 +0000

Diabetes is one of the life threatening metabolic disorders that has no cure but only management. Various therapeutic agents are available in nature which can aid in blood sugar management. However role of Mango in diabetes was always known to be negative and thought to increase blood sugar levels. Objective of the study is to test the therapeutic role of Mango leaf extract in diabetic control. The anti diabetic effect of leaf extract was studied based on the principle of alpha glucosidase enzyme inhibition test. Further, secondary metabolites present in leaf extract were analyzed biochemically. Antimicrobial potential of the extract was studied against 4 test bacteria which included Escherichia coli, Enterobacter spp, Pseudomonas aeroginosa and Staphylococcus aureus. Kirby bauer’s method of disc diffusion was used for this assay. All the results of the study were analyzed to confirm the therapeutic potential of mango leaves.

A Review Report on Epidemiology, Etiology and Prophylaxis of Malaria and the Life cycle of Plasmodium

Noor Nihad Abdul Hussein — Mon, 31 Oct 2022 00:00:00 +0000

Malaria is a parasite disease transmitted by mosquitoes that can be fatal. Malaria affects around 40% of the world's population, mostly those living in the world's poorest nations (undeveloped and developing). There are also alarming signs that malaria is spreading to new parts of the globe and resurfacing in previously eradicated locations. This review article brings awareness about its various aspects in terms of its epidemiology, symptoms, causes, diagnosis and treatment. The information related to the life cycle of the parasite, sources of infection, mechanism behind the disease are well discussed to have a clear understanding of the disease and the parasite. Preliminary symptoms to identify the disease and various diagnostic protocols to confirm the infection are explained. By highlighting the statistics of the disease, its prevalence and spread has been described and importance of preventing the infection is focused. Malaria can be lethal if the causative protozoa infect and destroy red blood cells (anemia) or clog the capillaries that supplies blood (cerebral malaria) or other essential organs. Malaria must be identified early in order to treat the patient in a timely manner and to prevent the transmission of infection further in the community via mosquitoes.

Isolation and identification of probiotic bacteria from home made and commercial curd

Pavani Sure — Mon, 31 Oct 2022 00:00:00 +0000

Bacteria have always been the most abundant living creatures on earth which may be either helpful to humans in the form of single cell proteins, probiotics, natural gut flora or many a times be harmful and cause several infections becoming fatal. Application of these bacteria and their natural process for the development and well being of humans is the major focus of several researchers. Importance of probiotic bacteria has long been known to the mankind and has been the study subject. The current work involves isolation and identification of different bacteria from selected probiotic food. Since curd is the most natural and probiotic rich food consumed most commonly it has been selected for the study. This study included selective study of microbes in commercial and home made curd. The focus is to summarize the common microbes in both commercial and home made curd and to identify if any special organisms are included in the commercial curd. The bacterial identification after isolation is mainly based on molecular techniques like sequencing and BLAST assay for high end accuracy.